Mississippi Starting Point:  At US 49/US 49E in Yazoo City, Yazoo County
Mississippi Ending Point:  At US 49/US 49E/MS 3 in Tutwiler, Tallahatchie County
Official Length (MDOT):  79.141 miles (has changed since publication)

Mississippi Counties:  Yazoo, Humphreys, Sunflower, Coahoma, Tallahatchie
Cities/towns over 5,000 pop served:  Yazoo City, Indianola

1.4 miles with MS 12 in Belzoni
0.2 miles with MS 442 in Doddsville
0.8 mile with MS 32 near Webb in Tallahatchie County

NHS:  From US 49 in Yazoo City to US 82 in Indianola

Freeway Segments:  None

Other Multilane Segments:
From US 49 in Yazoo City to just north of US 82

Average Daily Traffic (1998): Ranges from 2,000 in Tallahatchie County to 9,600 in Yazoo City.

Did not exist until 1932, when the US 49E/US 49W split was made. Southern section of this route was designated for 4-laning under the 1987 Highway Program, and was also marked as NHS.
NO trucks are allowed through Yazoo City.  Trucks must detour via routes on the edge of the city.
In 2004, a completely new 4-lane alignment between Yazoo City and Silver City opened.  This had the effect of lengthening US 49, shortening US 49W, and allowing trucks to follow US 49W without detouring around the middle of Yazoo City.

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